our Health Index for More Subjects, Conditions and
What does it mean when your blood test shows High B12 Levels?
I've talked to many people who are
told by their medical doctor that they found high
levels of B12 in their blood test. They are thus
reluctant to take a B vitamin formula designed to help
build healthy nerves as it has B12 in it. But, what
does this actually mean?
What other symptoms do you have?
High B12 levels in the blood can be
the result of liver disease, kidney failure and blood
cancers. There is also a condition where a person has
too many white blood cells that causes high vitamin
B12. These conditions, however, will all have other
symptoms other than this blood test result, and your
medical doctor will test if he suspects any of
A deficiency of vitamin B12, or a low
B12 level, can contribute to a wide range of problems.
General symptoms of vitamin B12 deficiency can include
tiredness, weakness, abdominal pain, nausea,
constipation, flatulence, reduction in appetite, and
Extended periods of deficiency can
eventually result in degeneration of nerves as the
body needs it to build the myelin sheath (outside of
the nerve). Those who suffer from a vitamin B12
deficiency can have tingling sensations numbness,
and burning feelings, weakness in the legs and
What happens when you have these
low B12 level symptoms but the blood tests
show high B12 levels?
Vitamin B12 does not accumulate to
toxic levels. Consuming large quantities does not
cause side effects or high levels in your system,
whether you get it through food or from taking
What is another cause of blood tests showing high
amounts of B12?
High serum B12 can be caused by a "functional" B12 deficiency. What does that
In that condition, there is enough B12
going into the body, but the cells are not able to use
it properly. This results in the body putting the B12
back in the blood. It builds up there bound to
haptocorrin. Haptocorrin is a Vitamin B12 binding
What happens when the body is not able
to use the B12 at a cellular level?
High serum B12 per se is not harmful,
but it indicates that there is an issue with B12
One reason for this is that B12 from
food and most supplements is the form cynocobalamine.
In order for the body to utilize it, it must be
converted to Methyl B 12 (or methylcobalamine). This
conversion happens in the gut. The
intrinsic factor is necessary for this
conversion. If a person doesn’t for any reason have
sufficient intrinsic factor, this will not take place
and the B12 will not be utilized.
Intrinsic factor: Intrinsic factor is a protein secreted by the stomach that joins vitamin B-12 in the stomach and escorts it through the small intestine to be absorbed by your bloodstream. Without intrinsic factor, vitamin B-12 can't be absorbed and leaves your body as waste.
Thus, high levels of B12 in a blood
test can be a "functional" B12 deficiency.
The intrinsic factor goes down with age, and thus as
we age we are less likely to be able to absorb the
B12 in our food and supplements.
For more information about a B12
If you have an actual functional B12
deficiency, it is important to supplement with Methyl
B12 which can be gotten from B12 shots or by
supplementing Methyl B12 which is like getting a B12
shot every day.
Sources of Methyl B12
Information about B
Or if you have nervous system
HAVE QUESTIONS? EMAIL
AND GET YOUR QUESTIONS ANSWERED.
If you would like to receive the
Sign up by clicking here: Newsletter Signup
take privacy and security seriously, read about it
Tips Health Concerns
McVitamins.com is an affiliate of Real
© 2000-2018 McVitamins.com
. All Rights Reserved. Reproduction of this website in full or in part is prohibited without the express written permission of McVitamins.com
We have used our best judgment in compiling this information. The Food and Drug Administration may not have evaluated the information presented. Any reference to a specific product is for your information only and is not intended to diagnose, treat, cure, or prevent any disease